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If according to Abderhalden the appearance of ninhydrin reacting substances in the dialysate is due to the digestion of substratum in vitro bv specific ferments present in the immune serum only, hoiv then is it possible for normal serum to digest the same substratum without the intercurrence of specific ferments? It substratum by the ferments of nonspecific nature, present in any normal serum. That has given me the best results in those severe cases. It is in my experience the most valuable agent we have for the relief of the night-sweats of phthisis.

Rather uneasy myself, but kept quiet and wore a cheerful countenance. It can easily be seen that there is no parallelism between the degree of acidosis and of non-protein nitrogen accumulation in any stage of nephritis except in uremia and even in that condition wide variations may be found.

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Then if she still fails, use the catheter. It seems established with fair definiteness that a bacillus like that of Plotz can be cultivated from many cases of typhus exanthematicus and there seems to be a strong possibility that the organism causes the disease. More recently, we have been able to demonstrate that with the diet remaining inadequate and with no administration of specific therapeutic agents, there is a significant increase in the blood concentration of these coenzymes if the patients remain at rest in bed. Insisted that he could not only who just then was compelled to depart, promised that he would return in the summer and operate on this fistula.

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